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How dangerous is nicotine?

Nicotine can act as a stimulant or as a sedative. Both of these effects are dose-dependent. But at higher doses, nicotine can cause hallucinations, or worse. Consider the fact that nicotine is an insecticide. Most insecticides are neurotoxic.  

This means they target the nervous system of insects in order to kill them. Many chemicals used for chemical warfare in World War I were neurotoxins first developed as insecticides, and these are still used as insecticides today.

Many plant and animal poisons are neurotoxins. So the question of whether or not nicotine is dangerous is a matter of dosing. When considering dosing, you should also consider potency-that is, how much of the drug is required to achieve its desired effect, and how much of the drug is required to kill you.

This is known in medicine as the therapeutic window; the narrower the therapeutic window, the more dangerous the drug. Nicotine is probably the most toxic substance regularly used by humans recreationally. It is far more toxic than even cocaine, which has been publicized in the media because of a number of famous people who have died from accidental overdose as well as stories of so-called mules, or people who died trying to smuggle the drug into the country.

They do this by placing it in balloons and swallowing it and receive a lethal dose should a balloon burst. It takes about 600 mg of cocaine to kill a man. It takes only about a tenth of that amount-60 mg-of nicotine to kill a man. A typical cigarette contains anywhere from 0.5 to 2 mg of nicotine. A line of cocaine contains about 35 to 40 mg of cocaine, depending upon its purity.

Nicotine - is probably the most toxic substance regularly used by humans recreationally.

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